The Simple Test Which May Help Prevent Autism
The Simple Test Which May Help Prevent Autism
Story at-a-glance
· A new hypothesis states that impaired glucose tolerance and hyperinsulinemia may be a common underlying mechanism of type 2 diabetes and autism
· Emerging research also suggests strong links between gut flora and both diabetes and brain disorders such as autism. The primary key to maintaining both healthy gut flora and optimal insulin levels is a low-fructose, low-carb diet, high in nutrient-dense whole foods
· Gut and Psychology Syndrome (GAPS) is the result of poorly developed or imbalanced gut flora, which can have a disastrous effect on mental health and brain development and function. Interestingly, children who do not develop normal gut flora from birth also appear to be particularly prone to vaccine damage, and this knowledge may be a MAJOR key for reducing vaccine injuries, including autism
· GAPS can be easily identified within the first weeks of your baby's life by analyzing his stool to determine the state of his gut flora, and a urine test to check for metabolites. These tests will provide a picture of the state of your child's immune system. If your child has abnormal gut flora, he will be more prone to vaccine damage, so avoiding inoculations until the metabolic characteristics of GAPS have been reversed is highly recommended
By Dr. Mercola
A review of genetic and biochemical abnormalities has revealed a possible link between autism and type 2 diabetes.
It's still only a hypothesis, but according to Rice University biochemist Michael Stern, author of the opinion paper, these two conditions may have a common underlying mechanism: impaired glucose tolerance and hyperinsulinemia.
Hyperinsulinemia, a common precursor to insulin resistance, is characterized by excess levels of insulin in your bloodstream.
Insulin resistance, in turn, is associated with type 2 diabetes, obesity, and many other chronic diseases.
Could it also be associated with autism?
"It will be very easy for clinicians to test my hypothesis.
They could do this by putting autistic children on low-carbohydrate diets that minimize insulin secretion and see if their symptoms improve."
Sterns hypothesis also suggests that glucose tolerance in pregnant women may need to be addressed more seriously than it is now, in order to decrease the child's risk of autism.
"... [A]t least four genes associated with increased frequency in autism are known to produce proteins that play key roles in a biochemical pathway known as PI3K/Tor ... PI3K/Tor [is] the major pathway for insulin signals within cells, and insulin [can] affect synapses in a remarkably similar way to the mGluR defects associated with autism.
… "I discovered that gestational diabetes was the most important identified maternal risk factor for autism, but that 'no known mechanism could account for this,'" Stern recalled. "When I read this, I was speechless. That's when I realized that this was not obvious to others in the field, so I decided to write this up with the hope that clinicians might become aware of this and treat their patients accordingly."
In writing the article, Stern said he learned that the role of insulin in cognitive function is becoming more widely accepted… Stern said he also found preliminary studies that indicated that low-carb diets were therapeutic for some individuals with autism and ASD.
"Based on what's already in the literature, insulin needs to be taken seriously as a causative element in autism," Stern said."
Diabetes, Autism and... Gut Flora: A Hidden Connection?
Sterns hypothesis linking autism and type 2 diabetes is an interesting one, and although it may initially sound far-fetched, other research suggests he may very well be onto something, especially if we consider the emerging research linking gut flora to both diabetes and autism. Could it be that it's actually the gut microflora that is an underlying link between diabetes and autism?
There's no definitive evidence of this at the moment, but there appear to be some rather compelling "circumstantial evidence" leaning in that direction.
For example, researchers have found that bacterial populations in the gut of diabetics differ from non-diabetics, and imbalanced gut flora has also been linked to obesity and various brain- and mental disorders—from depression to autism.
Interestingly, obesity and diabetes appear to be associated with different bacterial populations according to one 2010 study. While the researchers found a positive correlation between ratios of Bacteroidetes to Firmicutes and BMI, the reverse tendency was observed in those with diabetes, indicating that obesity and diabetes are associated with different groups of intestinal microbiota. They also found a positive correlation for the ratios of Bacteroidetes to Firmicutes and reduced glucose tolerance.
The Gut-Brain Connection—A Hidden Key to Solving Autism Mystery?
In terms of treatment, Sterns hypothesis ends up coinciding quite nicely with the GAPS theory put forth by Dr. Natasha Campbell-McBride. The low-carbohydrate diet he recommends will automatically help rebalance your child's gut flora, and Dr. Campbell-McBride's nutritional program has the identical focus.
Dr. Campbell-McBride has a full-time medical practice in the United Kingdom where she treats children and adults with autism and other neurological disorders, immune disorders, and digestive problems. Her groundbreaking research led her to create the Gut and Psychology Syndrome (GAPS) Nutritional Program, which can help those with autism, ADHD, dyslexia, dyspraxia, depression and schizophrenia.
What is GAPS?
GAPS is the result of poorly developed or imbalanced gut flora, which can have a disastrous effect on mental health and brain development and function.
Interestingly, children who do not develop normal gut flora from birth also appear to be particularly prone to vaccine damage, and this may be a MAJOR key for reducing vaccine injuries. Dr. Campbell is actually convinced that autistic children are born with perfectly normal brains and sensory organs, but once their digestive system becomes a major source of toxicity instead of being a source of nourishment, they start to develop autistic symptoms. A vaccine may simply "push them over the edge."
Another group of children that may also over-react to vaccinations are siblings of children with autism, severe hyperactivity, obsessive compulsive disorder, mental conditions, and—again—type 1diabetes.
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